Our group is interested in studying of the ways in which small molecules interact with each other and their surroundings. By gaining an understanding of molecular association events, we can learn to design and control receptor - substrate binding and self-assembly events, and even control fundamental chemical properties such as solubility which are critically important in numerous fields of study.
Work in the Haynes group is particularly focussed on the application of supramolecular chemistry to biological and medicinal chemistry problems, such as controlling pharmacokinetic parameters via tuning non-covalent interactions, the design of novel amphiphiles to yield responsive self-assembled nanostructures for the controlled uptake, transport and release of guests. Our group also aims to develop molecular tools that are stimuli-responsive to a range of biomarkers and light.