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Publications

Lipid headgroup binding.JPG

Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of ‘druggable’ supramolecular self-associating antimicrobial amphiphiles

J. E. Boles, C. Bennett, J. Baker, K. L. F. Hilton, H. A. Kotak, E. R. Clark, Y. Long, L. J. White, H.-Y. Lai, C. K. Hind, J. M. Sutton, M. D. Garrett, A. Cheasty, J. L. Ortega-Roldan, M. Charles, C. J. E. Haynes and J. R. Hiscock

Chem. Sci. 2022,13, 9761–9773.

Water soluble potassium transporter.JPG

A water-soluble membrane transporter for biologically relevant cations

K. Yang, J. Boles, L. White, K. Hilton, H.-Y. Lai, Y. Long, J. R. Hiscock and C. J. E. Haynes

RSC Advances, 2022, 12, 27877–27880.

Coord chem rev.JPG

Metal-organic ion transport systems

​K. Yang, H. A. Kotak and C. J. E. Haynes

Coord. Chem. Rev. 2022, 470, 214705.

Applied technologies.JPG

Advances in applied supramolecular technologies

G. T. Williams, C. J. E. Haynes, M. Fares, C. Caltagirone, J. R. Hiscock and P. A. Gale

Chem. Soc. Rev. 2021, 50, 2737–2763.

Optical biosensors.JPG

Supramolecular Coordination Complexes as Optical Biosensors

N. Dey and C. J. E. Haynes

ChemPlusChem 2021, 86, 418–433.

Cally's previous work (Cambridge, Southampton, Oxford)

FeII4L4 tetrahedron binds and aggregates DNA G-quadruplexes

J. Zhu, Z. Yan, F. Bošković, C. J. E. Haynes, M. Kieffer, J. L. Greenfield, J. R. Nitschke and U. F. Keyser

Chem. Sci. 2021, 12, 14564–1456.

Guest Encapsulation Within Surface-Adsorbed Self-Assembled Cages

H. P. Ryan, C. J. E. Haynes, A. Smith, A. B. Grommet and J. R. Nitschke

Adv. Mat. 2021, 33, 2004192.

Coordination cages as permanently porous ionic liquids

L. Ma, C. J. E. Haynes, A. B. Grommet, A. Walczak, C. C. Parkins, C. M. Doherty, L. Longley, A. Tron, A. R. Stefankiewicz, T. D. Bennett and J. R. Nitschke

Nat. Chem. 2020, 12, 270–275.

FeII4L4 Tetrahedron Binds to Nonpaired DNA Bases

J. Zhu, C. J. E. Haynes, M. Kieffer, J. L. Greenfield, R. D. Greenhalgh, J. R. Nitschke, and U. F. Keyser

J. Am. Chem. Soc. 2019, 141, 11358–11362.

Embedding and positioning of two FeII4L4 cages in supramolecular tripeptide gels for selective chemical segregation

M. Kieffer, A. M. Garcia, C. J. E. Haynes, S. Kralj, D. Iglesias, J. R. Nitschke and S. Marchesan

Angew. Chem. Int. Ed. 2019, 58, 7982–7986.

Orthogonal stimuli trigger self-assembly and phase transfer of Fe4L4 cages and cargoes

A. J. McConnell, C. J. E. Haynes, A. B. Grommet, C. M. Aitchison, J. Guilleme, S. Mikutis and J. R. Nitschke

J. Am. Chem. Soc. 2018, 140, 16952–16956.

Full elucidation of the transmembrane anion transport mechanism of squaramides using in silico investigations

I. Marques,  P. M. R. Costa,  M. Q. Miranda,  N. Busschaert,  E. N. W. Howe,  H. J. Clarke,  C. J. E. Haynes,  I. L. Kirby,  A. M. Rodilla,  R. Pérez-Tomás,  P. A. Gale  and  V. Félix

Phys. Chem. Chem. Phys., 2018, 20, 20796–20811.

Giant M2L3 metallo-organic helicate based on phthalocyanines as a host for electroactive molecules

E. Fazzio, C. J. E. Haynes, G. de la Torre, J. R. Nitschke and T. Torres

Chem. Commun., 2018, 54, 2651–2654.

Blockable Zn10L15 ion channels via subcomponent self-assembly

C. J. E. Haynes, J. Zhu, C. Chimerel, S. Hernández-Ainsa, I. A. Riddell, T. K. Ronson, U. F. Keyser and J. R. Nitschke

Angew. Chem. Int. Ed., 2017, 56, 15388–15392.

QSAR analysis of substituent effects on tambjamine anion transporters

N. J. Knight, E. Hernando, C. J. E. Haynes, N. Busschaert, H. J. Clarke, K. Takimoto, M. Garcia-Valverde, J. G. Frey, R. Quesada and P. A. Gale

Chem. Sci., 2016, 7, 1600–1608.

Anion binding and transport properties of cyclic 2,6-bis(1,2,3-triazol-1-yl)pyridines

​T. Merckx, C. J. E. Haynes, L. E. Karagiannidis, H. J. Clarke, K. Holder, A. Kelly, G. J. Tizzard, S. J. Coles, P. Verwilst, P. A. Gale and W. Dehaen

Org. Biomol. Chem., 2015, 13, 1654–1661.

Highly effective yet simple transmembrane anion transporters based upon ortho-phenylenediamine bis-ureas

L. E. Karagiannidis, C. J. E. Haynes, K. J. Holder, I. L. Kirby, S. J. Moore, N, J. Wells and P. A. Gale

Chem. Commun., 2014, 50, 12050–12053.

Anion receptor chemistry: highlights from 2011 and 2012

P. A. Gale, N. Busschaert, C. J. E. Haynes, L. E. Karagiannidis and I. L. Kirby

Chem. Soc. Rev., 2014, 43, 205-241.

Lipophillic balance– a new design principle for transmembrane anion carriers

H. Valkenier, C. J. E. Haynes, P. A. Gale and A. P. Davies

Chem. Sci., 2014, 5, 1128–1134.

Synthetic transporters for sulfate: a new method for the direct detection of lipid bilayer sulfate transport

N. Busschaert, L. E. Karagiannidis, M. Wenzel, C. J. E. Haynes, N. J. Wells, P. G. Young, D. Makuc, J. Plavec, K. A. Jolliffe and P. A. Gale

Chem. Sci., 2014, 5, 1118–1127.

Acyl thioureas as anion transporters: the role of intramolecular hydrogen bonding

C. J. E. Haynes, N. Busschaert, I. L. Kirby, J. Herniman, M. E. Light, N. J. Wells, I. Marques, V. Félix and P. A. Gale

Org. Biomol. Chem., 2014, 12, 62–72.

Towards predictable transmembrane anion transport: QSAR analysis of anion binding and transport properties of thioureas

N. Busschaert, S. J. Bradberry, M. Wenzel, C. J. E. Haynes, J. R. Hiscock, I. L. Kirby, L. E. Karagiannidis, S. J. Moore, N. J. Wells, J. Herniman, G. J. Langley, P. N. Horton, M. E. Light, I. Marques, P. J. Costa, V. Félix, J. G. Frey and P. A. Gale

Chem. Sci., 2013, 4, 3036–3045.

Small neutral molecular carriers for selective carboxylate transport

C. J. E. Haynes, S. N. Berry, J. Garric, J. Herniman, J. R. Hiscock, I. L. Kirby, M. E. Light, G. Perkes and P. A. Gale

Chem. Commun., 2013, 49, 246-248.

Anion recognition and transport properties of sulfamide-, phosphoric triamide- and thiophosphoric triamide-based receptors

​P. B. Cranwell, J. R. Hiscock, C. J. E. Haynes, M. E. Light, N. J. Wells and P. A. Gale

Chem. Sci., 2013, 49, 874–876.

Chloride, carboxylate and carbonate transport by ortho-phenylenediamine-based bisureas

S. J. Moore, C. J. E. Haynes, J. González, J. L. Sutton, S. J. Brookes, M. E. Light, J. Herniman, G. J. Langley, V. Soto-Carrato, R. Pérez-Tomás, I. Marques, P. J. Costa, V. Félix and P. A. Gale

Chem. Sci., 2013, 4, 103–117.

Oligoether-Strapped Calix[4]pyrrole: An Ion-Pair Receptor Displaying Cation-Dependent Chloride Anion Transport

I.-W. Park, J. Yoo, B. Kim, S. Adhikari, S. K. Kim, Y. Yeon, C. J. E. Haynes, J. L. Sutton, C. C. Tong, V. M. Lynch, J. L. Sessler, P. A. Gale and C.-H. Lee

Chem. Eur. J., 2012, 18, 2514–2523.

Tunable transmembrane chloride transport by bis-indolylureas

C. J. E. Haynes, S. J. Moore, J. R. Hiscock, I. Marques, P. J. Costa, V. Félix and P. A. Gale

Chem. Sci., 2012, 3, 1436–1444.

Transmembrane anion transport by synthetic systems

C. J. E. Haynes and P. A. Gale

Chem. Commun., 2011, 47, 8203–8209.

Structurally simple lipid bilayer transport agents for chloride and bicarbonate

N. J. Andrews, C. J. E. Haynes, M. E. Light, S. J. Moore, C. C. Tong, J. T. Davis, W. A. Harrell Jr. and P. A. Gale

Chem. Sci,, 2011, 2, 256–260.

Tripodal transmembrane transporters for bicarbonate

N. Busschaert, P. A. Gale, C. J. E. Haynes, M. E. Light, S. J. Moore, C. C. Tong, J. T. Davis and W. A. Harrell Jr.

Chem. Commun., 2010, 46, 6252–6254.

Octafluorocalix[4]pyrrole: A chloride/bicarbonate antiport agent

P. A. Gale, C. C. Tong, C. J. E. Haynes, O. Adeosun, D. E. Gross, E. Karnas, E. M. Sedenberg, R. Quesada and J. L. Sessler

J. Am. Chem. Soc., 2010, 132, 3240–3241.

​Comparative structural and thermodynamic studies of fluoride and cyanide binding by PhBMes2 and related triarylborane Lewis acids

C. Bresner, C. J. E. Haynes, D. A. Addy, A. E. J. Broomsgrove, P. Fitzpatrick, D. Vidovic, A. L. Thompson, I. A. Fallis and S. Aldridge

New J. Chem., 2010, 34, 1652–1659.

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